Department of
Biological Chemistry & Molecular Pharmacology

Morphogenesis and organogenesis

Welcome Bender

Professor
Telephone: 
617-432-1906
Fax: 
617-738-0516
Address: 
Room C - 203
Address: 
240 Longwood Avenue
Address: 
Boston MA 02115

The bithorax complex in the fruit fly is a cluster of “homeotic” genes which confer distinct identities on the different segments of the fly. The genes are strikingly aligned on the DNA in the order of the segments they affect. The genes, and their alignment, are conserved from nematodes to humans. Many of the interactions of bithorax mutations are difficult to explain with the known forms of transcriptional regulation. The paradoxes hopefully reflect novel molecular mechanisms.

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George Daley

Professor
Telephone: 
617-919-2015
Fax: 
617-730-0222
Address: 
Children's Hospital
Address: 
300 Longwood Ave.
Address: 
Boston, MA 02115

The laboratory focuses on stem cell biology, with an emphasis on hematopoietic differentiation from human and mouse pluripotent stem cells (embryonic stem, ES, and induced Pluirpotent Stem, iPS) cells, epigenetic reprogramming, germ cell development, and the overlap between germ cells, stem cells and cancer. Our goals are described briefly below:

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Andrew Lassar

Professor
Telephone: 
617- 432-3831
Fax: 
617-738-0516
Address: 
Room C1 -303
Address: 
240 Longwood Avenue
Address: 
Boston, MA 02115

Current work in my lab focuses on the signals and transcription factors that maintain skeletal muscle stem cells, the transcriptional regulatory pathways that regulates chondrocyte formation and maturation, and the development of a gene therapy model to treat osteoarthritis:
 

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