Department of
Biological Chemistry & Molecular Pharmacology

Mechanobiology

Wesley P. Wong

Assistant Professor
Telephone: 
617-713-8383
Fax: 
617-713-8393
Address: 
Immune Disease Institute
Address: 
Harvard Medical School Affiliate
Address: 
3 Blackfan Circle, 3rd floor
Address: 
Boston, MA 02115

We are interested in understanding the physical basis of how biological systems work at the nanoscale, with a focus on the role of mechanical force. More specifically, we investigate how force regulates the structure and dynamics of interactions between and within single-molecules, and how this in turn can affect the functioning and malfunctioning of biological systems. To accomplish this, my group develops and applies novel tools in single-molecule manipulation and detection, combining approaches from a variety of disciplines, including physics, molecular biology, chemistry, and engineering. Some key research projects that we are working on are highlighted below.

1. Novel high-throughput methods in single-molecule manipulation, including single-molecule centrifugation

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