Department of
Biological Chemistry & Molecular Pharmacology

Evolution

Shamil Sunyaev

Assistant Professor
Telephone: 
617-525-4735
Fax: 
617-525-4705
Address: 
New Research Building, Room 466b
Address: 
77 Avenue Louis Pasteur
Address: 
Boston, MA 02115

We are a computational biology laboratory. We develop and apply computational methods to pursue various problems in fields of genetics, genomics and proteomics. Our main interest is to analyze the population genetic variation and the genome divergence between species with the major focus on the protein coding regions. The effect of amino acid substitutions on function and structure of proteins can be frequently understood and even predicted via comparative sequence analysis and analysis of the protein structure. We relate the above functional studies to the evolutionary process of natural selection in order to track the evolution of proteins at the molecular level.

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