Department of
Biological Chemistry & Molecular Pharmacology

Cytoskeleton / extracellular matrix interactions / cell adhesion

Elaine Elion

Professor
Telephone: 
617-432-3815
Fax: 
617-738-0516
Address: 
Room C1-302
Address: 
240 Longwood Avenue
Address: 
Boston MA 02115

Our group studies eukaryotic signal transduction, focusing on how external stimuli control proliferation, differentiation, and homeostasis. Work has centered on defining how mitogen activated protein kinase (MAPK) cascades function in vivo. MAPK cascades form the cores of numerous eukaryotic signal transduction pathways that control growth, differentiation and survival. Misregulation of MAPK cascades is associated with a variety of diseases, including cancer. We use a yeast model system (Figure 1) and genetic, biochemical and cell biological approaches.

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