Department of
Biological Chemistry & Molecular Pharmacology

Dominic M. Walsh

Associate Professor
Center for Neurologic Diseases
Brigham & Women's Hospital
77 Avenue Louis Pasteur, HIM 921
Boston, MA 02115

Dominic M. Walsh, Ph.D., is an Associate Professor at Brigham & Women’s Hospital and Harvard Medical School, and visiting Professor at the Institute of Neurology at University College London.  He began working on Alzheimer’s disease in 1992 and gained postdoctoral training in Ireland and the US.  With support from the Wellcome Trust he established the Laboratory for Neurodegenerative Research at University College Dublin in 2003 and in September 2011 moved his lab to the Harvard Institutes of Medicine in Boston. In 2014, he was named as one of the world's most influencial scientific minds by Thomson Reuters, and is ranked among the top 1% of researchers in the field of Neuroscience and Behavior.

Prof. Walsh’s lab applies a wide range of advanced biochemical, molecular, cell biological, electrophysiological and behavioural methods to decipher the basic mechanisms of neurodegeneration.  The ultimate goal of his research is to generate sufficient information to allow the development of rationally designed drugs that will slow or halt disease.  As such he has been at the forefront of studies on the role of soluble Aβ oligomers in Alzheimer's disease and has authored several landmark papers.  The impact and pace of his work is evident from the fact that twenty of his publications have each been cited in access of 200 times and that more than forty were published since 2010.  Prof. Walsh has also written a number of widely cited reviews and has given over 80 invited lectures and webinars.  He has served as an Editor or Editorial Advisor for several journals and as an ad hoc reviewer for all of the world’s leading biomedical journals.  His research has been supported by the Wellcome Trust, European Union, Science Foundation Ireland, Health Research Board, IRCSET, Medical Research Council (UK), NIH (USA), Cure Alzheimer's Fund, Fidelity Biosciences Research Initiative, Alzheimer’s Association (USA), BrightFocus, Harvard NeuroDiscovery, the Binational Science Foundation, and grants from industry and donations from the general public.

Prof. Walsh has provided expert analysis of Alzheimer disease research on TV and radio and has worked tirelessly to highlight the need for more investment in clinical and research services.  He was the co-founder of the Dublin Brain Bank and was a member of the Irish National Steering Committee on Neurodegenerative Disease Research.  Prof. Walsh has also organized several international conferences and has acted as a grant reviewer for more than 20 different agencies in the US, Europe, middle-East and Australia.  He has served on the scientific advisory board of several start-up companies and is a consultant to a number of leading pharmaceutical companies.